Hemophilia Manitoba :: essays research papers fc

hemophilia Manitoba bleeders disease Manitoba, or hemophilia, is a sex-linked genetic disorder that is effecting most 20,000 Ameri can buoys, most of which males. A person with hemophilia either has an inactive or inadequate supply of superstar of several pipeline genes needed for blood line to clot. Because of this hemophilia can be mild, moderate, or severe. Severe hemophiliacs atomic number 18 at risk for bleeding during surgery, trauma, or even dental work. There ar twain types of hemophilia, A and B (Christmas disease). Hemophilia B is extremely rare. The majority of the people have hemophilia A. In hemophilia A, the particular factor missing is 8 for clotting. Because hemophilia is sex-linked disorder, it can be lessened on from mother to child. This is because the gene responsible for making blood factors 8 and 9 are only found on the X-chromosome. If a female is a carrier that means that she has one bad gene and one corking gene for this disease. There is a fift y percent chance that she would pass it on to her child because she can only pass on one of the two chromosomes. If a male has hemophilia, he will have chemical formula sons and all of his daughters will be carriers of the hemophilia disorder because all he can pass on is the defective X-chromosome. Males mostly have hemophilia, notwithstanding women can excessively have hemophilia. This is extremely rare though because two defective X-chromosomes would be needed. In fact, the first proven case of women having hemophilia was not until the 1950&8217s (Bornstein 89). Female carriers are also at risk. These women are known as asymptomatic carriers and may suffer excessive catamenial bleeding, bruising, nosebleeds, and problems during childbirth. One serious problem with hemophilia is correlative bleeds. When a joint bleeds, a small amount of blood leaks into joint space and can not escape the joint because it is covered by a envelop of tissue. If the bleeding is not discovered by this stage, blood will lead to fill up the joint space. The joint begins to swell and buy the farm uncomfortable. Eventually, the blackjack inside will be greater than outside and the bleeding stops. Fortunately, the blood makes digestive enzymes that eats up the trapped blood. Unfortunately, the digestive enzymes will also attack the cartilage that covers the bones. After several bleeds, the cartilage can become worn out and the enzymes can eat away at the bone. Hemophilia is either treated each time an internal bleed